Publications Archive

Explore peer-reviewed articles, research papers, and academic contributions from GSK members.

8 Total7 Categories2023 Latest

8 Publications

Sorted by year (newest first)
Infectious Diseases2023

Prevalence and Risk Factors of Helicobacter pylori Infection in Kenya: A Cross-Sectional Study

Authors: Kimani J, Ogutu E, Wangari M, Maina D, Njoroge M, Waweru W, et al.

East African Medical Journal, 2023

This cross-sectional study investigated the prevalence and risk factors of Helicobacter pylori infection in various regions of Kenya. Over 1,200 participants from both urban and rural settings were included in the analysis, which identified socioeconomic factors, water sources, and household crowding as significant risk factors for H. pylori positivity.

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Endoscopy2022

Endoscopic Management of Gastrointestinal Bleeding: A Retrospective Analysis of Cases in Nairobi

Authors: Omondi L, Njoroge P, Kamau W, Otieno G, Mwangi J, Waihenya R, et al.

World Journal of Gastroenterology, 2022

This retrospective study analyzed 450 cases of gastrointestinal bleeding managed endoscopically at three tertiary hospitals in Nairobi. The research evaluated the etiology, treatment outcomes, and factors associated with rebleeding, highlighting the effectiveness of various endoscopic techniques in the Kenyan healthcare context.

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Hepatology2022

Hepatitis B Vaccination Coverage Among Healthcare Workers in Kenyan Hospitals

Authors: Mwangi A, Githinji G, Wanjiku C, Nganga L, Kariuki S, et al.

Journal of Viral Hepatitis, 2022

This study assessed hepatitis B vaccination coverage among healthcare workers in 24 hospitals across Kenya. The research identified significant gaps in vaccination coverage, particularly among non-clinical staff, and explored barriers to vaccination including vaccine availability, cost, and institutional policies.

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Oncology2021

Colorectal Cancer Screening Practices in Kenya: Challenges and Opportunities

Authors: Ndegwa S, Kariuki P, Otieno F, Gatheru P, Miriti K, et al.

African Journal of Cancer, 2021

This review examined current practices, challenges, and opportunities for colorectal cancer screening in Kenya. The study highlighted low screening rates, limited resources, and poor awareness as major barriers, while proposing culturally-appropriate strategies to increase screening uptake in the population.

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Inflammatory Bowel Disease2021

Clinical Presentation and Management of Inflammatory Bowel Disease: Experience from a Nairobi Cohort

Authors: Gitau W, Muriithi A, Otieno Y, Mwangi N, Litu O, et al.

Inflammatory Bowel Diseases, 2021

This prospective study described the clinical presentation, diagnostic approaches, and management strategies for inflammatory bowel disease in a cohort of 85 patients in Nairobi. The research highlighted distinctive patterns of disease presentation and treatment challenges in the Kenyan context.

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Hepatology2020

Prevalence of Non-Alcoholic Fatty Liver Disease in Urban Kenya and Associated Metabolic Risk Factors

Authors: Karanja J, Waiganjo N, Mbugua S, Odhiambo K, et al.

BMC Gastroenterology, 2020

This study investigated the prevalence of non-alcoholic fatty liver disease in an urban Kenyan population and its association with metabolic syndrome components. Using ultrasound and laboratory evaluation of 712 participants, the research identified a rising prevalence and associated risk factors in this previously understudied population.

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Esophageal Disorders2020

Prevalence of Barrett's Esophagus in Patients Undergoing Upper Endoscopy in Kenya

Authors: Ngugi P, Mwaniki J, Njeru E, Waweru P, et al.

Diseases of the Esophagus, 2020

This prospective study determined the prevalence of Barrett's esophagus among 430 patients undergoing upper endoscopy at two referral hospitals in Kenya. The research identified prevalence, associated risk factors, and highlighted challenges in diagnosis and surveillance in resource-limited settings.

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Gastroenterology2019

Peptic Ulcer Disease and NSAID Use in Kenya: A Hospital-Based Case-Control Study

Authors: Okoth K, Akelo V, Mulwa E, Mwaura J, et al.

Pan African Medical Journal, 2019

This case-control study examined the relationship between non-steroidal anti-inflammatory drug (NSAID) use and peptic ulcer disease in a Kenyan hospital setting. The research quantified risk factors and patterns of NSAID use, providing evidence for preventing NSAID-associated upper gastrointestinal complications.

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